Weight-based Drug Doses






Drug Calcualted Dose Route Indication
Adrenaline (10 µg/kg) IV/IO, IM, ET Cardiac arrest, bradycardia with poor perfusion, anaphylaxis (1 µg/kg IV)
Amiodarone (5 mg/kg) IV/IO Ventricular fibrillation or pulseless ventricular tachycardia unresponsive to defibrillation and CPR
Defibrillation (4 j/kg) External pads Ventricular fibrillation or pulseless ventricular tachycardia
Cardioversion (1 j/kg) External pads Synchronised Shock, 1.0 joules/kg escalating to 2.0 joules/kg if unsuccessful
Atropine (20 µg/kg) IV/IO Bradycardia (after adequate ventilation and oxygenation), pulseless electrical activity (PEA) with suspected vagal tone
Adenosine (100 µg/kg) Intravenous SVT, up to 1 year: 150 µg\kg, increase 50-100 µg\kg every 1-2 min. Maximum single dose: Neonates 300 µg\kg, Infants 500 µg\kg
Magnesium (25-50 mg\kg) Intravenous in Torsades de pointes VT, maximum per dose 2 g to be given over 10-15 min, may be repeated once if necessary
Calcium Gluconate (0.5 ml/kg) Intravenous Hypocalcaemia, hyperkalaemia (max dose 20 mL); IV over 2-5 min if unstable, over 15-20 min if stable
Fluid bolus (10 ml/kg) Intravenous Balanced isotonic crystalloid or 0.9% Saline
Gucose (2 ml/kg) Intravenous Glucose 10%
Sodium bicarbonate (1 mmol/kg) Intravenous Sodium Bicarbonate 8.4%, for infants under 3-month-old use 4.2% (2 ml/kg)
Drug Calcualted Dose Indication
Adrenaline (1 µg/kg) Treat hypotension with small epinephrine dose (max 1 µ/kg)
Intralipid 20% bolus (1.5 ml/kg) Administer intravenous Intralipid as an initial bolus over a minute
Start infusion (0.25 ml/kg/min) Start an infusion of 20% lipid emulsion at 0.25 ml/kg/min
Increase infusion to (0.5 ml/kg/min) Increase the infusion to 0.5 ml/kg/min if cardiovascular stability is not restored
Repeat bolus Repeat bolus every 3-5 min up to 4.5 mL/kg total dose until circulation is restored (total of 3 boluses)
Total dose (10 ml/kg) The total dose should not exceed 10ml/kg
Dantrolene Dose
Initial Bolus (2.5 mg/kg) mg
Repeat Boluses (1 mg/kg) mg every 5-10 minutes
Total Dose (10 mg/kg) mg
Remaining Dose mg